Cancer Vaccine
Moderna and Merck's vaccine prevents melanoma return
Georgina Long / Moderna / Merck /

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Last Updated
9/15/2026
Articles
136
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The Breakdown 98

  • Moderna and Merck have unveiled a groundbreaking personalized mRNA cancer vaccine, Intismeran, that dramatically reduces the recurrence and spread of melanoma in high-risk patients following surgery.
  • The Phase 3 clinical trial results are a major milestone, showcasing the vaccine's effectiveness when combined with Merck's immunotherapy, Keytruda.
  • Following the announcement, Moderna's stock skyrocketed by as much as 177%, underscoring the immense financial potential of this breakthrough in cancer treatment.
  • Led by renowned Australian researcher Georgina Long, the trial represents a significant advancement in personalized medicine, demonstrating how targeted therapies can train the immune system to combat specific tumor mutations.
  • Experts are optimistic that this innovative approach could not only transform melanoma care but also pave the way for effective vaccines against other types of cancer.
  • While initial results are promising, further data and regulatory approvals are essential before this revolutionary treatment can become widely available to patients in need.

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Georgina Long / Chicago, United States / Moderna / Merck / Northwestern Medicine / NYU Langone / Johns Hopkins Medicine / Keytruda /

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